2015年1月4日下午3：00，美国威斯康星大学吴建强教授应beat365官方网站邀请在生物楼101教室做了题目为“肿瘤表观遗传学简介及其他”的学术报告，并与beat365官方网站师生进行了热烈地讨论。报告由莫日根教授主持。吴建强教授主要从事肿瘤发生机理以及防治肿瘤的新方法和新药物开发等领域的研究。主持多项包括NIH的研究项目，发表的主要学术论文有：
1. Wu J., Salva K., Wood GS. c-CBL E3 Ubiquitin Ligase is Over-Expressed in Cutaneous T-Cell Lymphoma: Its Inhibition Promotes Activation Induced Cell Death Journal of Investigative Dermatology, doi: 10.1038
2. Wu J., Wood GS. Quantitative Analysis of Gene Methylation and Corresponding Protein Expression by Specific Cell Types in Archival Tissue Sections. Experimental Dermatology, 23(5):304-9.
3. Wu J., Wood GS.Reduction of Fas/CD95 Promoter Methylation, Upregulation of Fas Protein, and Enhancement of Sensitivity to Apoptosis in Cutaneous T-Cell Lymphoma. Archives of Dermatology. 2011;147: 443-449.
4. Wu J., Siddiqui J, Nihal M, Vonderheid EC, Wood GS. Structural alterations of the FAS gene in cutaneous T-cell lymphoma (CTCL). Archives of Biochemistry and Biophysics. 2011; 508: 185-191
6. Wu J., Sheibani N. Modulation of VE-cadherin and PECAM-1 mediated cell-cell adhesion by mitogen-activated kinase. Journal of Cellular Biochemistry. 2003, 90:121-137.
7. Yang, B, O’herrin, S, Wu, J., Reagan-Shaw S, Ma Y, Bhat KM, Gravekamp C, Setaluri V, Peters N, Hoffmann FM, Peng H, Ivanov AV, Simpson AJ, Longley BJ. MAGE-A, mMage-b, and MAGE-C proteins form complexes with KAP1 and suppress p53-dependent apoptosis in MAGE-positive cell lines. Cancer Research. 2007, 67: 9954-9962.
8. Yang, B; Wu, J., Maddodi N, Ma Y, Setaluri V, Longley BJ. Epigenetic control of MAGE gene expression by the KIT tyrosine kinase. Journal of Investigative Dermatology.. 2007;127:2123-2128.
9. Yang, B; O’herrin, S; Wu, J; Reagan-Shan, S; Ma, Y; Nihal, M; Longley, BJ. Select Cancer Testes Antigens of the MAGE-A, -B, and -C Families Are Expressed in Mast Cell Lines and Promote Cell Viability In Vitro and In Vivo. Journal of Investigative Dermatology. 2007;127: :267-275.
10.Aziz M., Reagan-Shaw S., Wu J , Longley BJ, Ahmad N. Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease? FASEB J. 2005;19:1193-1195.
11.Wu, J., Wood G. Regulation of FAS Expression in Cutaneous T-Cell Lymphoma. Journal of Investigative Dermatology. 2011;131:21
12.Wu, J., Wood, G. Restoring FAS expression by reversing FAS promoter methylation: a novel approach to CTCL therapy. Journal of Investigative Dermatology. 2010; 130: 29-31
13.Wu, J., Wood, G. Genetic abnormalities associated with FAS-low CTCL. Journal of Investigative Dermatology. 2009; 129:33
14.Findley H, Wu J,. Gu L. Expression of Fas and Bcl-2 by Childhood Acute Lymphoblastic Leukemia Cells：Involvement of Bcl-2 in Fas Mediated Apoptosis. Blood 1995; 12: 263.
蒙ICP16002391号-1 